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L-Phenylalanine-d<sub>5</sub>

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2480

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9

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8

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1

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9

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10

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2410

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3

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0215S3
    L-Phenylalanine-d2

    (S)-2-Amino-3-phenylpropionic acid-d<sub>2sub>

    		 Calcium Channel iGluR Endogenous Metabolite Metabolic Disease
    L-Phenylalanine-d2 is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
    <em>L-Phenylalanine</em>-d2
  • HY-N0215S1
    L-Phenylalanine-d8

    (S)-2-Amino-3-phenylpropionic acid-d<sub>8sub>

    		 Calcium Channel iGluR Endogenous Metabolite Metabolic Disease
    L-Phenylalanine-d8 is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
    <em>L-Phenylalanine</em>-d8
  • HY-N0215S12
    L-Phenylalanine-d5

    		Calcium Channel iGluR Endogenous Metabolite Metabolic Disease
    L-Phenylalanine-d5 is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
    <em>L-Phenylalanine</em>-d<em>5</em>
  • HY-N0215S13
    L-Phenylalanine-d1

    (S)-2-Amino-3-phenylpropionic acid-d<sub>1sub>

    		 Isotope-Labeled Compounds Calcium Channel iGluR Endogenous Metabolite Metabolic Disease
    L-Phenylalanine-d is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
    <em>L-Phenylalanine</em>-d1
  • HY-N0215S
    L-Phenylalanine-d7

    (S)-2-Amino-3-phenylpropionic acid-d<sub>7sub>

    		 Isotope-Labeled Compounds Calcium Channel iGluR Endogenous Metabolite Metabolic Disease
    L-Phenylalanine-d7 is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
    <em>L-Phenylalanine</em>-d7
  • HY-RS13999
    SUB1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SUB1 Human Pre-designed siRNA Set A
    SUB1 Human Pre-designed siRNA Set A
  • HY-146227
    DNA topoisomerase II inhibitor 1

    		Topoisomerase Apoptosis Cancer
    DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .
    DNA topoisomerase II inhibitor 1
  • HY-N0215S6
    DL-Phenylalanine-d5 hydrochloride

    2-Amino-3-phenylpropionic acid-d<sub>5sub> hydrochloride

    		 Isotope-Labeled Compounds Calcium Channel iGluR Endogenous Metabolite Metabolic Disease
    DL-Phenylalanine-d5 (hydrochloride) is the deuterium labeled DL-Phenylalanine hydrochloride. L-Phenylalanine hydrochloride is an essential amino acid isolated from Escherichia coli. L-Phenylalanine hydrochloride is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine hydrochloride is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine hydrochloride is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
    DL-<em>Phenylalanine</em>-d<em>5</em> hydrochloride
  • HY-N0215S9
    L-Phenylalanine-13C9,15N,d8

    (S)-2-Amino-3-phenylpropionic acid-13C<sub>9sub>,15N,d<sub>8sub>

    		 Isotope-Labeled Compounds Calcium Channel iGluR Endogenous Metabolite Metabolic Disease
    L-Phenylalanine- 13C9, 15N,d8 is the deuterium, 13C-, and 15-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
    L-<em>Phenylalanine</em>-13C9,15N,d8
  • HY-N0215S10
    L-Phenylalanine-13C9

    (S)-2-Amino-3-phenylpropionic acid-13C<sub>9sub>

    		 Isotope-Labeled Compounds Calcium Channel iGluR Endogenous Metabolite Metabolic Disease
    L-Phenylalanine- 13C9 is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
    L-<em>Phenylalanine</em>-13C9
  • HY-N0215S8
    L-Phenylalanine-13C6

    (S)-2-Amino-3-phenylpropionic acid-13C<sub>6sub>

    		 Isotope-Labeled Compounds Calcium Channel iGluR Endogenous Metabolite Metabolic Disease
    L-Phenylalanine- 13C6 is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
    L-<em>Phenylalanine</em>-13C6
  • HY-N0215S14
    L-Phenylalanine-15N,d8

    (S)-2-Amino-3-phenylpropionic acid-15N,d<sub>8sub>

    		 Isotope-Labeled Compounds Calcium Channel iGluR Endogenous Metabolite Metabolic Disease
    L-Phenylalanine- 15N,d8 is the deuterium and 15N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca2+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
    L-<em>Phenylalanine</em>-15N,d8
  • HY-N0215S11
    L-Phenylalanine-13C9,15N

    (S)-2-Amino-3-phenylpropionic acid-13C<sub>9sub>,15N

    		 Calcium Channel iGluR Endogenous Metabolite Metabolic Disease
    L-Phenylalanine- 13C9, 15N is the 13C- and 15N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
    L-<em>Phenylalanine</em>-13C9,15N
  • HY-B0184S1
    Felbamate-d5

    Felbamyl-d<sub>5sub>; Felbatol-d<sub>5sub>; Taloxa-d<sub>5sub>

    		 iGluR Neurological Disease
    Felbamate-d5 is the deuterium labeled Felbamate[1]. Felbamate (W-554) is a potent nonsedative anticonvulsant whose clinical effect may be related to the inhibition of N-methyl-D-aspartate (NMDA)[2][3].
    Felbamate-d<em>5</em>
  • HY-16560S
    Camptothecin-d5

    Campathecin-d<sub>5sub>; (S)-(+)-Camptothecin-d<sub>5sub>; CPT-d<sub>5sub>

    		 Topoisomerase ADC Cytotoxin MicroRNA Influenza Virus Apoptosis Fungal Antibiotic Infection Cancer
    Camptothecin-d5 is the deuterium labeled Camptothecin. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM[1]. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells[2][3].
    Camptothecin-d<em>5</em>
  • HY-B0715S2
    Pentoxifylline-d5

    BL-191-d<sub>5sub>; PTX-d<sub>5sub>; Oxpentifylline-d<sub>5sub>

    		 Phosphodiesterase (PDE) Autophagy HIV Cardiovascular Disease Cancer
    Pentoxifylline-d5 is the deuterium labeled Pentoxifylline. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation[1][2][3].
    Pentoxifylline-d<em>5</em>
  • HY-107819S
    5α-Cholestan-3β-ol-d5

    Dihydrocholesterol-d<sub>5sub>; 5α-Cholestanol-d<sub>5sub>; NSC 18188-d<sub>5sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite
    5α-Cholestan-3β-ol-d5 is the deuterium labeled 5α-Cholestan-3β-ol. 5α-Cholestan-3β-ol is a derivitized steroid compound[1].
    <em>5</em>α-Cholestan-3β-ol-d<em>5</em>
  • HY-N0573S
    Umbelliferone-d5

    7-Hydroxycoumarin-d<sub>5sub>; Hydrangin-d<sub>5sub>; NSC 19790-d<sub>5sub>

    		 Endogenous Metabolite Apoptosis Cancer
    Umbelliferone-d5 is the deuterium labeled Umbelliferone. Umbelliferone (7-Hydroxycoumarin), a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent.
    Umbelliferone-d<em>5</em>
  • HY-W022036S
    2-Ethoxyphenol-d5

    Guaethol-d<sub>5sub>; Guethol-d<sub>5sub>; NSC 180-d<sub>5sub>

    		 Isotope-Labeled Compounds Others
    2-Ethoxyphenol-d5 is the deuterium labeled 2-Ethoxyphenol[1].
    2-Ethoxyphenol-d<em>5</em>
  • HY-66005S5
    Acetaminophen-d5

    Paracetamol-d<sub>5sub>; 4-Acetamidophenol-d<sub>5sub>; 4'-Hydroxyacetanilide-d<sub>5sub>

    		 Isotope-Labeled Compounds Others
    Acetaminophen-d5 is deuterated-labeled Acetaminophen.
    Acetaminophen-d<em>5</em>
  • HY-B1207S
    Urethane-d5

    Ethyl carbamate-d<sub>5sub>; Carbamic acid ethyl ester-d<sub>5sub>; Ethylurethane-d<sub>5sub>

    		 Bacterial Parasite Infection Neurological Disease Cancer
    Urethane-d5 is the deuterium labeled Urethane. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro[1].
    Urethane-d<em>5</em>
  • HY-77839S
    Cortodoxone-d5

    11-Deoxycortisol-d<sub>5sub>; cortexolone-d<sub>5sub>; Reichstein's substance S-d<sub>5sub>

    		 Isotope-Labeled Compounds Glucocorticoid Receptor Endogenous Metabolite Inflammation/Immunology Endocrinology
    Cortodoxone-d5 is the deuterium labeled Cortodoxone.
    Cortodoxone-d<em>5</em>
  • HY-14814S
    Delafloxacin-d5

    RX-3341-d<sub>5sub>; WQ-3034-d<sub>5sub>; ABT492-d<sub>5sub>

    		 Isotope-Labeled Compounds Bacterial Antibiotic Infection
    Delafloxacin-d5 is deuterium labeled Delafloxacin. Delafloxacin (RX-3341; WQ-3034; ABT492) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumonia[1].
    Delafloxacin-d<em>5</em>
  • HY-13636S1
    Fulvestrant-d5

    ICI 182780-d<sub>5sub>; ZD 9238-d<sub>5sub>; ZM 182780-d<sub>5sub>

    		 Isotope-Labeled Compounds Others
    Fulvestrant-d5 is a isotope of Fulvestrant .
    Fulvestrant-d<em>5</em>
  • HY-B0200S
    Cephalexin-d5

    Cefalexin-d<sub>5sub>; Cephacillin-d<sub>5sub>

    		 Antibiotic Bacterial Infection
    Cephalexin-d5 is deuterium labeled Cephalexin. Cephalexin (Cefalexin; Cephacillin) is a potent, orally active and the first-generation cephalosporin antibiotic. Cephalexin kills gram-positive and some gram-negative bacteria by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al[1].
    Cephalexin-d<em>5</em>
  • HY-B0178AS1
    Guanidine-d5 hydrochloride

    Guanidinium-d<sub>5sub> chloride; Aminoformamidine-d<sub>5sub> hydrochloride

    		 Endogenous Metabolite
    Guanidine-d5 (hydrochloride) is the deuterium labeled Guanidine hydrochloride[1]. Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins[2][3].
    Guanidine-d<em>5</em> hydrochloride
  • HY-N0570S1
    Hydroxytyrosol-d5

    DOPET-d<sub>5sub>; 3,4-Dihydroxyphenethyl alcohol-d<sub>5sub>; 3-Hydroxytyrosol-d<sub>5sub>

    		 Endogenous Metabolite Bacterial Fungal Infection Inflammation/Immunology Cancer
    Hydroxytyrosol-d5 is the deuterium labeled Hydroxytyrosol. Hydroxytyrosol (DOPET) is a phenolic compound drawn from the olive tree and its leaves with anti-oxidant, anti-atherogenic, anti-thrombotic, antimicrobial, anti-inflammatory and anti-tumour effects[1][2].
    Hydroxytyrosol-d<em>5</em>
  • HY-B0941S
    6-Benzylaminopurine-d5

    Benzyladenine-d<sub>5sub>; 6-BAP-d<sub>5sub>; N6-Benzyladenine-d<sub>5sub>

    		 Endogenous Metabolite Isotope-Labeled Compounds Others
    6-Benzylaminopurine-d5 is the deuterium labeled 6-Benzylaminopurine. 6-Benzylaminopurine is a cytokinin[1].
    6-Benzylaminopurine-d<em>5</em>
  • HY-B0878S
    Halobetasol propionate-d5

    BMY-30056-d<sub>5sub>; CGP-14458-d<sub>5sub>; Ulobetasol propionate-d<sub>5sub>

    		 Isotope-Labeled Compounds Others
    Halobetasol propionate-d5 is deuterium labeled Halobetasol (propionate).
    Halobetasol propionate-d<em>5</em>
  • HY-B1290S2
    2-Phenylethanol-d5

    Phenylethyl alcohol-d<sub>5sub>; Phenethyl alcohol-d<sub>5sub>; Benzyl carbinol-d<sub>5sub>

    		 Bacterial Virus Protease Antibiotic Infection
    2-Phenylethanol-d5 is the deuterium labeled 2-Phenylethanol[1]. 2-Phenylethanol (Phenethyl alcohol), extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid. It has a pleasant floral odor and also an autoantibiotic produced by the fungus Candida albicans[2]. It is used as an additive in cigarettes and also used as a preservative in soaps due to its stability in basic conditions.
    2-Phenylethanol-d<em>5</em>
  • HY-B0346S
    Propylthiouracil-d5

    6-n-Propylthiouracil-d<sub>5sub>; 6-Propyl-2-thiouracil-d<sub>5sub>; PTU-d<sub>5sub>

    		 Isotope-Labeled Compounds Endocrinology
    Propylthiouracil-d5 is the deuterium labeled Propylthiouracil. Propylthiouracil (6-Propyl-2-thiouracil) is a thyroperoxidase and 5'-deiodinase inhibitor.
    Propylthiouracil-d<em>5</em>
  • HY-12222S
    Obeticholic acid-d5

    INT-747-d<sub>5sub>; 6-ECDCA-d<sub>5sub>; 6-Ethylchenodeoxycholic acid-d<sub>5sub>

    		 FXR Autophagy Others
    Obeticholic acid-d5 is the deuterium labeled Obeticholic acid. Obeticholic acid (INT-747) is a potent, selective and orally active FXR agonist with an EC50 of 99 nM. Obeticholic acid has anticholeretic and anti-inflammation effect. Obeticholic acid also induces autophagy[1][2][3].
    Obeticholic acid-d<em>5</em>
  • HY-12760S
    Indoramin-d5

    Indoramine d<sub>5sub>; Wy-21901 d<sub>5sub>

    		 Isotope-Labeled Compounds Adrenergic Receptor Cardiovascular Disease
    Indoramin-d5 is deuterium labeled Indoramin, which is a piperidine antiadrenergic agent.
    Indoramin-d<em>5</em>
  • HY-14648S
    Dexamethasone-d5

    Hexadecadrol-d<sub>5sub>; Prednisolone F-d<sub>5sub>

    		 Glucocorticoid Receptor SARS-CoV Autophagy Complement System Mitophagy Bacterial Antibiotic Infection Inflammation/Immunology Endocrinology Cancer
    Dexamethasone-d5 is the deuterium labeled Dexamethasone. Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses[1][2].
    Dexamethasone-d<em>5</em>
  • HY-17043S1
    Loratadine-d5

    Loratidine-d<sub>5sub>; SCH 29851-d<sub>5sub>

    		 Isotope-Labeled Compounds Histamine Receptor Infection Inflammation/Immunology Endocrinology
    Loratadine-d5 is the deuterium labeled Loratadine. Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity. Loratadine can inhibit immunologic release of inflammatory mediators.
    Loratadine-d<em>5</em>
  • HY-141642S
    Triheptadecanoin-d5

    Glycerol triheptadecanoate-d<sub>5sub>; Trimargarin-d<sub>5sub>

    		 Isotope-Labeled Compounds Others
    Triheptadecanoin-d5 is the deuterium labeled Triheptadecanoin[1].
    Triheptadecanoin-d<em>5</em>
  • HY-B0521S
    Altrenogest-d5

    Allyltrenbolone-d<sub>5sub>; RU2267-d<sub>5sub>

    		 Progesterone Receptor Endocrinology
    Altrenogest-d5 is the deuterium labeled Altrenogest. Altrenogest (Allyltrenbolone) is a progestogen structurally related to veterinary steroid trenbolone.
    Altrenogest-d<em>5</em>
  • HY-N0623S
    L-Tryptophan-d5

    Tryptophan-d<sub>5sub>; Tryptophane-d<sub>5sub>

    		 Endogenous Metabolite Metabolic Disease
    L-Tryptophan-d5 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].
    L-Tryptophan-d<em>5</em>
  • HY-109592S
    Imidaprilate-d5

    6366A-d<sub>5sub>; Imidaprilat-d<sub>5sub>

    		 Isotope-Labeled Compounds Angiotensin-converting Enzyme (ACE) Cardiovascular Disease
    Imidaprilate-d5 is deuterium labeled Imidaprilate. Imidaprilate is an active metabolite of TA-6366, acts as a potent angiotensin converting enzyme (ACE) inhibitor, with an IC50 of 2.6 nM, and is used in the research of hypertensive disease.
    Imidaprilate-d<em>5</em>
  • HY-B0808S1
    Oxaprozin-d5

    Oxaprozinum-d<sub>5sub>; Wy21743-d<sub>5sub>

    		 Isotope-Labeled Compounds COX NF-κB Inflammation/Immunology Cancer
    Oxaprozin-d5 is deuterium labeled Oxaprozin. Oxaprozin is an inhibitor of both COX-1 and COX-2 with IC50s of 2.2 μM and 36 μM for human platelet COX-1 and IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-κB.
    Oxaprozin-d<em>5</em>
  • HY-125833
    Alpha-Naphthoflavone
    5 Publications Verification

    		 Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis Cancer
    Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis .
    Alpha-Naphthoflavone
  • HY-B0141S2
    Estradiol-d5

    β-Estradiol-d<sub>5sub>; 17β-Estradiol-d<sub>5sub>; 17β-Oestradiol-d<sub>5sub>

    		 Estrogen Receptor/ERR Endogenous Metabolite Endocrinology Cancer
    Estradiol-d5 is deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3].
    Estradiol-d<em>5</em>
  • HY-14649S4
    Retinoic acid-d5

    Vitamin A acid-d<sub>5sub>; all-trans-Retinoic acid-d<sub>5sub>; ATRA-d<sub>5sub>

    		 Isotope-Labeled Compounds RAR/RXR PPAR Cancer
    Retinoic acid-d5 is the the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha [5].
    Retinoic acid-d<em>5</em>
  • HY-17357S
    Nepafenac-d5

    AHR-9434-d<sub>5sub>; AL-6515-d<sub>5sub>

    		 COX Others
    Nepafenac-d5 is the deuterium labeled Nepafenac, which is a selective COX-2 inhibitor.
    Nepafenac-d<em>5</em>
  • HY-B0660S
    Eicosapentaenoic Acid-d5

    EPA-d<sub>5sub>; Timnodonic acid-d<sub>5sub>

    		 Endogenous Metabolite Histone Demethylase Neurological Disease Cancer
    Eicosapentaenoic Acid-d5 is the deuterium labeled Eicosapentaenoic Acid. Eicosapentaenoic Acid (EPA; Timnodonic acid) is an omega-3 fatty acid.
    Eicosapentaenoic Acid-d<em>5</em>
  • HY-10162S
    Olaparib-d5

    AZD2281-d<sub>5sub>; KU0059436-d<sub>5sub>

    		 PARP Autophagy Mitophagy Cancer
    Olaparib-d5 is a deuterium labeled Olaparib. Olaparib is a potent and oral PARP inhibitor[1].
    Olaparib-d<em>5</em>
  • HY-13026S
    Idelalisib-d5

    CAL-101 d<sub>5sub>; GS-1101 d<sub>5sub>

    		 PI3K Autophagy Cancer
    Idelalisib-d5 is a deuterium labeled Idelalisib. Idelalisib is a highly selective and orally bioavailable p110δ inhibitor[1].
    Idelalisib-d<em>5</em>
  • HY-B0002BS
    Ondansetron-d5

    GR 38032-d<sub>5sub>; SN 307-d<sub>5sub>

    		 5-HT Receptor Neurological Disease
    Ondansetron-d5 is the deuterium labeled Ondansetron. Ondansetron (GR 38032; SN 307) is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy.
    Ondansetron-d<em>5</em>
  • HY-107850S
    Pregnanediol-d5

    NSC 1612-d<sub>5sub>; NSC 47462-d<sub>5sub>

    		 Endogenous Metabolite Metabolic Disease
    Pregnanediol-d5 is the deuterium labeled Pregnanediol. Pregnanediol is the major metabolite of progesterone and can be excreted via urine. Pregnanediol offers an indirect way to measure progesterone levels in vivo[1].
    Pregnanediol-d<em>5</em>
  • HY-15315S
    Baricitinib-d5

    LY3009104-d<sub>5sub>; INCB028050-d<sub>5sub>

    		 JAK Inflammation/Immunology
    Baricitinib-d5 is the deuterium labeled Baricitinib. Baricitinib (LY3009104; INCB028050) is a selective and orally bioavailable JAK1 and JAK2 inhibitor with IC50s of 5.9 nM and 5.7 nM, respectively.
    Baricitinib-d<em>5</em>

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